The Loss of USAID is Killing People

In Defense of USAID, Part 2.

Since I wrote my last article, the indiscriminate gutting of USAID and the Federal government writ large has continued unabated and with reckless abandon for costs and consequences. I know many friends and former colleagues that have lost their jobs— people that are kind, intelligent, hard-working, and dedicated to the public good, not “corrupt” or “lazy” as Elon Musk would have you believe. But then again Mr. Musk doesn’t care about the fate of government workers or any of the good that USAID did because he believes “The fundamental weakness of Western civilization is empathy” as he said in an interview with Joe Rogan on Feb 28, 2025. Makes sense, because destroying USAID will literally kill people, and only someone devoid of empathy could possibly be ok with that.

The real cost to the death of USAID and American goodness abroad will be measured in bodies. This is not exaggeration or metaphor, I am being as literal as I can possibly be. Cutting USAID will kill people–IS killing people—and the most likely culprit is HIV/AIDS.

There are a million examples of foreign aid programs doing good things: nutrition and food programs to fight famines,  disaster recovery after a tsunami or earthquake, supporting refugee camps for those fleeing war, water and sanitation programs, programs combating gender-based violence, programs improving schools and hospitals, and so many more. I am going to focus on the biggest and probably the most successful foreign aid program in history – the President’s Emergency Fund for AIDS Relief or PEPFAR.

PEPFAR is a massive program that has saved 25 million lives from HIV over the last 20 years. While the program encompasses several agencies including the Department of State, the Centers for Disease Control and others, USAID is the primary implementer of the program. As one global health expert said, the loss of funding for program “will be a bloodbath.”

The number of HIV deaths have fallen since the start of PEPFAR in 2003.

PEPFAR was created in 2003 under the George W. Bush Administration. In the 90s and early 2000s, HIV was a true pandemic that rampaged across the globe. New antiviral treatments and public health campaigns combating the virus had huge benefits to fighting the disease in the U.S., but for lower income countries, the virus was left virtually unchecked, for example, killing tens of millions in Africa. As American lives and treasure were wasted in the middle-East wars fueled by post-9-11 hysteria, the Bush Administration at least recognized the benefits of foreign aid in promoting American values (this is a perfect example of the contradictions of U.S. foreign policy I alluded to in the last article). Bush signed the United States Leadership Against HIV/AIDS, Tuberculosis, and Malaria Act of 2003 on May 27, 2003, created PEPFAR (as well as programs for countering tuberculosis and malaria).

An Infographic from PEPFAR’s website summarizing its achievements.

PEPFAR has been an unambiguous success (and used to have wide-spread bipartisan support) and helped change the trajectory of the disease. There has  been a 39% decline in new HIV infections since 2010 and AIDS-related deaths have been reduced by 69% since the peak in 2004 and by 51% since 2010. The drop in HIV infections in Africa has largely been credited to USAID‘s stewardship of the program. Indeed, countries that have received PEPFAR aid have lower mortality rates compared to non-PEPFAR countries, providing strong evidence that the program DOES work.

Mortality has fallen in countries receiving PEPFAR aid since the start of the program in 2003.

For the cynics out there, what do we get out of it? Besides that obvious, that PEPFAR’s efforts have led to a significant reduction in new HIV infections globally, decreasing the likelihood of the virus spreading and worsening the situation in the United States, many economic benefits have been documented. For example, PEPFAR funding has been associated with increased employment, particularly among males in sub-Saharan African countries, contributing to economic growth and stability. Further, healthier populations in Africa have led to more robust economies, creating new markets for U.S. exports and fostering economic partnerships. But I don’t want to spend draw out this line of thinking because personally, I think saving 25 million lives is justification enough for the program. I wonder if Mr. Musk would agree.

The USAID stop work order and dismantling of the agency have already caused disruptions and threaten to undo the decade of progress in fighting the forgotten pandemic. In 2024, more than 20 million people were receiving HIV treatment through PEPFAR and nearly 84 million tested for HIV. Many countries, especially in Africa, lack the funding to cover HIV treatments and testing, hence why the generosity of the US and other nations is so important. The sudden cessation of funding has had an immediate impact as HIV testing and treatment centers are already closing and patients are no longer receiving their life-saving medications. One estimate says as many as 1,650,000 people could die within a year without American foreign aid for H.I.V. prevention and treatment.

Published in the New York Times (March 15, 2025)

Mr. Musk claimed that not a single life has been lost. The New York Times posted an analysis of how wrong this is. The article opens with the story of 10-year old Peter Donde who had died since he was unable to get his HIV medications. I’ll quote part of the article here: 

Peter Donde was a 10-year-old infected with H.I.V. from his mother during childbirth. But American aid kept Peter strong even as his parents died from AIDS. A program started by President George W. Bush called PEPFAR saved 26 million lives from AIDS, and one was Peter’s.

Under PEPFAR, an outreach health worker ensured that Peter and other AIDS orphans got their medicines. Then in January, Trump and Musk effectively shuttered the U.S. Agency for International Development, perhaps illegally, and that PEPFAR outreach program ended. Orphans were on their own.

Without the help of the community health worker, Peter was unable to get his medicines, so he became sick and died in late February, according to Moses Okeny Labani, a health outreach worker who helped manage care for Peter and 144 other vulnerable children.

The immediate cause of death was an opportunistic pneumonia infection as Peter’s viral load increased and his immunity diminished, said Labani.

“If U.S.A.I.D. would be here, Peter Donde would not have died,” Labani said.

This is just one life tragically and unnecessarily lost because of Mr. Musk and Mr. Trump’s actions. The true impact on human life may not be known for many years but there will be many, many more stories like Peter’s. Ironically, the loss of funding will hit Musk’s home country of South Africa particularly hard. One HIV expert said “I predict a huge disaster” in regards to the rise of infections and deaths there. Global Health used to be an issue of bi-partisan support. What congressman doesn’t love to brag about saving lives? But now Mr. Trump’s stronghold has forced his party to abandon their values, if they had any to begin with.

Mr. Musk, you killed Peter Donde. How many more will die because of your actions?

Trump and Musk Attack Biomedical Research

While the country enjoyed its annual celebration of the Super Bowl, the U.S. biomedical research sector was stabbed in the back.

Late last week, Trump slashed billions in funding overnight with no planning or consultations with researchers, doctors, or hospitals. The impact will be catastrophic for biomedical research: labs will shut down, clinical trials could get cancelled, and hospital staff fired.

What did they actually do?

The Trump Administration announced they would cap the amount of overhead that the National Institutes of Health (NIH), the largest funder of biomedical research in the world, is allowed to issue in research grants at 15%. Historically, the NIH has paid up to the ~50% range. If it goes through, this change would amount to a near immediate loss of billions of dollars to hospitals and universities, many in red states that voted for Trump.

So what do overhead costs cover? It’s estimated that for every dollar spent on planning and conducting  research, another is needed for facility and support staff costs.  Meaning, overhead pays for literally everything necessary for a lab to actually DO the research. This includes:

  • Buildings  costs
  • Advanced equipment & infrastructure
  • Utility costs
  • Health insurance & benefits

NIH funding also supports about 412,000 jobs, from research assistants to grant managers to people who dispose of toxic chemicals.

All of this is labeled by Musk and his goons as unnecessary waste as they continue their ill conceived rampage against the federal government and a strong American future.

The message is clear and destabilizing to the scientific ecosystem:  Your work is not valued. Your job is expendable. Patients don’t need new treatments.

Now is the time to inform and act — because the average person will not feel the near-term impact. But when the pipeline for new discoveries and new life-saving medications dries up, and America loses its position as the leader in biomedical innovation — we’ll ask “How did we let this happen??” 

The NIH is the engine that powers US medical innovation: long-term research with decades long horizons that companies and investors will never fund. Our economy gets a solid payback on this research — measurable in dollars, and immeasurable in lives.

For every $1 spent on NIH research, $2.46 flows back into our economy (Link1, Link2). Not to mention the taxes paid by a $1 Trillion biopharma and medical research industry. 

The discoveries made in these labs become tomorrow’s life-saving treatments. With healthcare costs spiraling, it is pennywise, pound foolish to slash research. 

Examples originating from the NIH: 

  • Cardiovascular disease: Advances in hypertension and cholesterol management reduced heart attack and stroke rates, saving $100s of billions. 
  • Cancer: research in precision medicine and immunotherapy has led to higher survival rates. Without foundational NIH funding, cancer immunotherapies wouldn’t exist.  
  • So many more!

Musk dares to call long-term investments in the fight against cancer a WASTE?

NIH’s indirect costs average (28%) and are in-line with private biotechs (25%-50%) and defense contractor overhead (10-100%) —  spending on facilities, equipment, infrastructure, benefits, project management, administration, etc.

Should we have oversight to ensure appropriate spending? Of course. But Musk’s surprise nuclear bomb is the WRONG way to approach this!

The NIH budget is:  

US long-term innovation is fueled by grants, and is the basis for our future economy (e.g. Internet, human genome, etc). The US has been the world’s beacon for medical research, attracting top talent and driving innovation. We’re about to dim that light. China just surpassed the US in annual research publicationsin the race for global dominance in medical research, these NIH cuts are like shooting researchers in the leg.

What do you value? For me, health research that saves lives ranks near the top. Do you agree? Speak. Up. Now. Lives depend on it.